Naturally Glass Walkers and Bone Gnawers are the two Tribes that are most represented inside of a Mega City. In fact, if one wishes to play anything other than those two tribes, with one exception, the player must come up with a damn good reason why a werewolf from another Tribe would be caught dead in the middle of a Sprawling expanse of Weaver wet dream.
The exception is a new camp of Uktena, Urban Uktena. The Camp came about not long after refugees started to pour into the Mega Cities, more accustomed to city living themselves prior to their change, and a cast off people in their own right, these Uktena kept to their Mystical ways and adapted to living a life inside an urban sprawl.
Werewolves can be cybernetically augmented, as well as getting Bioware, however this also reduces their connection to Gaia. They permanently lose a point of Gnosis for every implant they have (your max is 10). This is ontop of the normal drawbacks and negatives of having implants as per the rules for the Enhancement background. The exception to this rule is Fetish implants. Glass Walkers are the only tribe to actually condone fetish implants, and the max number of fetish implants you can have is half your Gnosis rating rounded down. In order to have Fetish Implants, you must have both the Fetish background, and Enhancement background (the Resources stipulation for Enhancement background stays the same).