Paradigm
The Progenitors dominate the field of modern medicine. Masters of the Sphere of Life, they employ the tools of genetic manipulation, hyper-advanced surgical techniques and sophisticated drugs to constantly push the envelope of medicine. They sometimes work closely with Iteration X, especially in the fields of cybertechnology and artificial body parts. Along with the Iterators they also provide the Union with a great many foot soldiers - genetically engineered clones designed to replace civilians are a stalwart, as are bioengineered horrors that guarded the most secret Technocratic labs.
Modernized
In 1851, the Hippocratic Circle, and the larger Order, underwent reorganization and emerged as the Technocratic Union. The Circle were re-christened as the Æsculpian Order. This lasted until the later years of the 19th century, when the Union overhauled itself yet again. The Æsculpians became the Progenitors.